NCP-CoV(2019-nCoV) Nucleocapsid Protein (His tag)





来源:Eukaryotic expression

表达宿主:HEK293 Cells

纯度:> 95 % as determined by SDS-PAGE.

内毒素:<1.0 EU per μg protein as determined by the LAL method.

蛋白构建:A DNA sequence encoding the 2019-nCOV Nucleocapsid Protein was expressed with a polyhistidine tag at the C-terminus.

生物活性:Testing in progress

分子量:The recombinant 2019-nCoV Nucleocapsid Protein (His tag) consists of 430 amino acids and predicts a molecular mass of 50kDa.


缓冲液: 20 mM Tris, 300 mM NaCl, 10 % glycerol, pH 8.0.(Please contact us for any concerns or special requirements.)

运输方式:Recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

稳定性&储存条件:Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

●2019-nCoV Nucleocapsid Protein (His tag): SDS-PAGE图片



●2019-nCoV Nucleocapsid Protein (His tag): 别称

coronavirus NP Protein, 2019-nCoV; coronavirus Nucleocapsid Protein, 2019-nCoV; coronavirus Nucleoprotein Protein, 2019-nCoV; cov np Protein, 2019-nCoV; ncov NP Protein, 2019-nCoV; novel coronavirus NP Protein, 2019-nCoV; novel coronavirus Nucleocapsid Protein, 2019-nCoV; novel coronavirus Nucleoprotein Protein, 2019-nCoV; np Protein, 2019-nCoV; nucleocapsid Protein, 2019-nCoV; Nucleoprotein Protein, 2019-nCoV

●CoV Nucleocapsid 背景信息

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.